Who decides that some biomarker is in good range, by averaging population, by some study, by looking at centenarians, and if biomarkers are there to show ideal health and metabolism it is not biomarkers for longevity, longevity is maybe different, that is different goal.
Maybe low body temperature is good for longevity, we don't know.
I searched some studies on this topic and got confronting conclusions.
Like you say everything he does maybe will do nothing for longevity (but being rich and low stress certainly will do 😁).
And the end if he was to be of better longevity down the line , how we will now why, maybe 95 percent of effects will be that gene therapy on remote island. We will not know.
I live at Mediterranean area, I can get real home made olive oil from people I know , yes that is more expensive than in stores.
It is just that I prefer butter, but I also use olive oil as much as butter.
Hi everyone. Bryan here 👋. Don't fall for Joseph’s trickery. He again distorts and contorts information. It’s clickbait.
Addressing all falsehoods would be endless and unproductive. Much of his content has gone stale as I’ve refuted his claims with data, but unlike legitimate journalists, he doesn’t issue corrections. He’s a content farmer.
Here is an example:
⬇️ I share my testosterone levels
⬇️ he accuses me of secretly using TRT
⬇️ I prove him wrong (LH & FSH results)
⬇️ he accuses me of lying
⬇️ I provide evidence with labs
⬇️ he ignores and still says I’m lying
It’s an endless rabbit hole. Joseph uses guilty-by-default tactics to spread conspiracy theories. He’s not an honest critic.
Another example, he says my sleep scores are impossible because of meetings with my CFO in China. I schedule meetings with my CFO when our time zones overlap. Pretty simple.
He repeatedly claims I hide data or cherry-pick results. This is false. I consistently publish full lab reports, historical data, and detailed health protocols openly on X. I even transparently share mistakes. For example, when a recent experiment backfired (a drug that unexpectedly sped up aging), I openly discussed it and adjusted course.
The irony is Joseph claims he wants more transparency, yet he weaponizes my openness. This is exactly the behavior that makes people hesitant to share publicly.
To further eliminate doubt, I published my complete, most recent biomarker panel. It included:
+ 60+ biomarkers
+ most recent results
+ average across 12 months
+ dates for everything
+ my blood draw from 4/1/25
+ the report directly from the lab
+ explanations on all markers
+ areas for improvement
Predictably, Joseph ignored this evidence because acknowledging it would undermine his narrative.
He argues Blueprint is a hidden profit scheme. This couldn't be further from the truth. I sold my previous company for $800M. If money were my motive, I wouldn’t choose to sell olive oil & protein. Our events (summits) run at a loss. I have openly stated that Blueprint is a pain in my ass. The headaches outweigh financial benefits. I fund it because I believe deeply in its value for my health & thousands of others.
Joseph claims we’re withholding BP5000 study data. All participants received their individual results and a summary of aggregate findings. During the study, our team confirmed that FDA regulations prohibit sharing raw study data (even anonymized) when it pertains to dietary supplements or foods, as this may be interpreted as making unauthorized health claims. We have strictly adhered to these regulatory guidelines & have provided scientifically accurate summaries within permissible boundaries.
He accused me of manipulating the Rejuvenation Olympics leaderboard. A third-party lab administers all aging-speed tests, & are the same for everyone: rankings are an average of your best three scores. This is to encourage experimentation. I personally have moved up & down the leaderboard, just like everyone else.
Lastly, Joseph directly benefits from attacking me. He makes Instagram reels to generate views, and to increase his followers and revenue. He isn’t creating this content for a noble cause: this is for self-interest. Joseph doesn’t have your back, he’s looking out for his own.
Who’s funding the months he spent working on these videos? His financial motives are unclear. He's previously faced scrutiny for not disclosing financial ties to the meat industry. I'm openly plant-based but have never imposed this choice on others. You do you.
It’s also amusing that Joseph claims my 8 months of 100% sleep must be fake because I'm an entrepreneur… as if consistently going to bed on time is some impossible feat. He provides no evidence for his claims. Meanwhile, I’ve published my data. I made sleep my #1 priority in life, and everyone in my orbit knows that.
We all know people like Joseph who say untrue things to harm reputations, driven by hidden motives. People who make ‘hit-and-run accusations’ & then don't clean up the mess they created when proven wrong. Hate will get you attention, but that doesn’t make it right.
Defamers don’t shape history; builders do. If you aim to positively impact the world, expect detractors like Joseph. They’re just noise.
Hey. Do you ever plan on creating content in Japanese? I would absolutely love having two versions of this to study and would definitely put money into that :)
I think this is a good example of why it’s hard to use money to get non-commodity goods. If you’re Bryan Johnson, you can personally do biohacking, and benefit from the lack of incentive to get wrong answers, and then if you’re as obsessive as Gwern or Clarence Bass you might end up with comparably interesting results. If you try to hire people to do it for you, *they* aren’t hundred-millionaires, so they *do* have an incentive to make this into a steady income for themselves, unless you demonstrate *exceptional* willingness to create different incentives: https://mediangroup.org/docs/the_professionals_dilemma.pdf
Usually people just don’t actually care that much, even if it seems like they ought to. The Open Philanthropy Project unfortunately is a similar story.
Who decides that some biomarker is in good range, by averaging population, by some study, by looking at centenarians, and if biomarkers are there to show ideal health and metabolism it is not biomarkers for longevity, longevity is maybe different, that is different goal.
Maybe low body temperature is good for longevity, we don't know.
I searched some studies on this topic and got confronting conclusions.
Like you say everything he does maybe will do nothing for longevity (but being rich and low stress certainly will do 😁).
And the end if he was to be of better longevity down the line , how we will now why, maybe 95 percent of effects will be that gene therapy on remote island. We will not know.
I live at Mediterranean area, I can get real home made olive oil from people I know , yes that is more expensive than in stores.
It is just that I prefer butter, but I also use olive oil as much as butter.
Hi everyone. Bryan here 👋. Don't fall for Joseph’s trickery. He again distorts and contorts information. It’s clickbait.
Addressing all falsehoods would be endless and unproductive. Much of his content has gone stale as I’ve refuted his claims with data, but unlike legitimate journalists, he doesn’t issue corrections. He’s a content farmer.
Here is an example:
⬇️ I share my testosterone levels
⬇️ he accuses me of secretly using TRT
⬇️ I prove him wrong (LH & FSH results)
⬇️ he accuses me of lying
⬇️ I provide evidence with labs
⬇️ he ignores and still says I’m lying
It’s an endless rabbit hole. Joseph uses guilty-by-default tactics to spread conspiracy theories. He’s not an honest critic.
Another example, he says my sleep scores are impossible because of meetings with my CFO in China. I schedule meetings with my CFO when our time zones overlap. Pretty simple.
He repeatedly claims I hide data or cherry-pick results. This is false. I consistently publish full lab reports, historical data, and detailed health protocols openly on X. I even transparently share mistakes. For example, when a recent experiment backfired (a drug that unexpectedly sped up aging), I openly discussed it and adjusted course.
The irony is Joseph claims he wants more transparency, yet he weaponizes my openness. This is exactly the behavior that makes people hesitant to share publicly.
To further eliminate doubt, I published my complete, most recent biomarker panel. It included:
+ 60+ biomarkers
+ most recent results
+ average across 12 months
+ dates for everything
+ my blood draw from 4/1/25
+ the report directly from the lab
+ explanations on all markers
+ areas for improvement
Predictably, Joseph ignored this evidence because acknowledging it would undermine his narrative.
He argues Blueprint is a hidden profit scheme. This couldn't be further from the truth. I sold my previous company for $800M. If money were my motive, I wouldn’t choose to sell olive oil & protein. Our events (summits) run at a loss. I have openly stated that Blueprint is a pain in my ass. The headaches outweigh financial benefits. I fund it because I believe deeply in its value for my health & thousands of others.
Joseph claims we’re withholding BP5000 study data. All participants received their individual results and a summary of aggregate findings. During the study, our team confirmed that FDA regulations prohibit sharing raw study data (even anonymized) when it pertains to dietary supplements or foods, as this may be interpreted as making unauthorized health claims. We have strictly adhered to these regulatory guidelines & have provided scientifically accurate summaries within permissible boundaries.
He accused me of manipulating the Rejuvenation Olympics leaderboard. A third-party lab administers all aging-speed tests, & are the same for everyone: rankings are an average of your best three scores. This is to encourage experimentation. I personally have moved up & down the leaderboard, just like everyone else.
Lastly, Joseph directly benefits from attacking me. He makes Instagram reels to generate views, and to increase his followers and revenue. He isn’t creating this content for a noble cause: this is for self-interest. Joseph doesn’t have your back, he’s looking out for his own.
Who’s funding the months he spent working on these videos? His financial motives are unclear. He's previously faced scrutiny for not disclosing financial ties to the meat industry. I'm openly plant-based but have never imposed this choice on others. You do you.
It’s also amusing that Joseph claims my 8 months of 100% sleep must be fake because I'm an entrepreneur… as if consistently going to bed on time is some impossible feat. He provides no evidence for his claims. Meanwhile, I’ve published my data. I made sleep my #1 priority in life, and everyone in my orbit knows that.
We all know people like Joseph who say untrue things to harm reputations, driven by hidden motives. People who make ‘hit-and-run accusations’ & then don't clean up the mess they created when proven wrong. Hate will get you attention, but that doesn’t make it right.
Defamers don’t shape history; builders do. If you aim to positively impact the world, expect detractors like Joseph. They’re just noise.
Stay strong. I have your back.
Hey. Do you ever plan on creating content in Japanese? I would absolutely love having two versions of this to study and would definitely put money into that :)
Debunking Bryan 'The Anorexic' Johnson. Speaking as Singapore’s Benjamin Button - please check out my PSA: www.deaging.guru/psa
I think this is a good example of why it’s hard to use money to get non-commodity goods. If you’re Bryan Johnson, you can personally do biohacking, and benefit from the lack of incentive to get wrong answers, and then if you’re as obsessive as Gwern or Clarence Bass you might end up with comparably interesting results. If you try to hire people to do it for you, *they* aren’t hundred-millionaires, so they *do* have an incentive to make this into a steady income for themselves, unless you demonstrate *exceptional* willingness to create different incentives: https://mediangroup.org/docs/the_professionals_dilemma.pdf
Usually people just don’t actually care that much, even if it seems like they ought to. The Open Philanthropy Project unfortunately is a similar story.